Inflammatoryboweldiseaseinducesinflammatoryandpre-neoplasticchangesintheprostate
炎症性肠病在前列腺中引起炎症和肿瘤前变化
Abstract
Background
Inflammatoryboweldisease(IBD)hasbeenimplicatedasariskfactorforprostatecancer,however,themechanismofhowIBDleadstoprostatetumorigenesisisnotknown.Here,weinvestigatedwhetherchronicintestinalinflammationleadstopro-inflammatorychangesassociatedwithtumorigenesisintheprostate.
背景
目前认为IBD是前列腺癌的危险因素，但是，IBD引发前列腺癌的机制尚不清楚。在这里，我们调查了慢性肠道炎症是否会导致与前列腺癌发生相关的促炎性变化。
Methods
UsingclinicalsamplesofmenwithIBDwhounderwentprostatectomy,weanalyzedwhetherprostatetumorshaddifferencesinlymphocyteinfiltrate